To evaluate the ability of newly identified clinical factors to predict prognosis and survival in idiopathic pulmonary fibrosis (IPF) and non-specific interstitial pneumonia (NSIP). METHODS: Seventy-eight patients referred to the University...
Fri 03 09 2010 Bibliographie
The purpose of this study was to identify the CT scan features that predict patient outcome after reexpansion procedures in patients with the fibrotic stage of endobronchial TB. METHODS: We retrospectively...
Fri 03 09 2010 Bibliographie
The association between venous thrombosis outside the splanchnic area as well arterial thromboembolism and the JAK2 V617F mutation, an important marker for chronic myeloproliferative neoplasms (MPN), is not completely clear. METHODS:...
Fri 03 09 2010 Bibliographie
The Pulmonary Embolism Severity Index (PESI) estimates the risk of 30-day mortality in patients with acute pulmonary embolism (PE). We constructed a simplified version of the PESI. METHODS: The study retrospectively...
Fri 03 09 2010 Bibliographie
To evaluate the ability of newly identified clinical factors to predict prognosis and survival in idiopathic pulmonary fibrosis (IPF) and non-specific interstitial pneumonia (NSIP). METHODS: Seventy-eight patients referred to the University...
Fri 03 09 2010 Bibliographie
Nosocomial pneumonia (NP) is a difficult diagnosis to establish in the critically ill patient due to the presence of underlying cardiopulmonary disorders (e.g., pulmonary contusion, acute respiratory distress syndrome, atelectasis)...
Fri 03 09 2010 Bibliographie
Allergy and allergens have been implicated in asthma and it has historically been assumed that deteriorating asthma is related to allergen exposure. In the current pro/con debate some ...
Thu 02 09 2010 Bibliographie
Studies have described individuals with combined pulmonary fibrosis and emphysema (CPFE), with preserved lung volumes, significant reductions in gas exchange, and high prevalence of pulmonary hypertension. While physiologic changes...
Thu 02 09 2010 Bibliographie
The combination of gemcitabine plus paclitaxel has been proposed as an alternative to the platinum-based combinations for treatment of advanced non-small-cell lung cancer (NSCLC). However, conflicting results have been...
Thu 02 09 2010 Bibliographie
There is a lack of consensus on factors that predict mortality in idiopathic pulmonary arterial hypertension (IPAH). Tests that can accurately predict prognosis are needed to guide treatment and counsel...
Thu 02 09 2010 Bibliographie
Large-cell neuroendocrine carcinoma is an aggressive variant of large-cell carcinoma of the lung, which has poor survival in most series, resembling that of small-cell lung carcinoma. We report our retrospective assessment...
Thu 02 09 2010 Bibliographie
Classical belief is that only smoking cessation, and not pharmacotherapy, beneficially affect disease progression in chronic obstructive pulmonary disease (COPD). In recent years, new data on pharmacotherapy of COPD became...
Wed 01 09 2010 Bibliographie
Conclusions The majority of patients with sleep-disordered breathing are using CPAP in the long term and the severity of sleep-disordered breathing rather than sleepiness determines long-term adherence to CPAP therapy. (Source:...
Wed 01 09 2010 Bibliographie
Conclusion The clinical impact of PPCs is marked. Significant independent preoperative risk factors have been identified in current clinical practice. Potentially modifiable risk factors include BMI, smoking status and COPD. The...
Wed 01 09 2010 Bibliographie
Conclusion In patients with stable asthma, bronchial reactivity is associated with HRQL. This could justify incorporating bronchial reactivity indices in bronchial provocation analyses. (Source: Thorax)
Wed 01 09 2010 Bibliographie
Summary: Tuberculosis (TB) is a major infectious disease killing nearly two million people, mostly in developing countries, every year. The increasing incidence of resistance of Mycobacterium tuberculosis strains to the...
Wed 01 09 2010 Bibliographie
Asthma is a common disease, and the number of people diagnosed with it increases every year. Although genetic background and environmental exposures play major roles in the development of...
Tue 31 08 2010 Bibliographie
Adenoidectomy is among the most frequent surgical procedures performed on children. The rationale for adenoidectomy is to remove a chronically infected or enlarged and obstructing adenoid. Adenoidectomies are performed...
Tue 31 08 2010 Bibliographie
Vitamin D insufficiency is common among Americans. The consequences of this phenomenon remain largely unknown; however, vitamin ...
Tue 31 08 2010 Bibliographie
The immunologic interactions in the gastrointestinal tract are extensive and complex. In most cases, the end result of this activity is one of tolerance, which refers to the inhibition...
Tue 31 08 2010 Bibliographie
Anaphylaxis is often managed inadequately. We used findings from a systematic review of gaps in anaphylaxis management to develop evidence-based recommendations for gaps rated as clinically important by a panel...
Tue 31 08 2010 Bibliographie
BACKGROUND: Research into the association between diabetes and pulmonary function has resulted in inconsistent outcomes among studies. We performed a metaanalysis to clarify this association. METHODS: From a systematic search of...
Mon 30 08 2010 Bibliographie
OBJECTIVE: To determine whether spirometry with regular medical review improves the quality of life or other health outcomes among patients with asthma or chronic obstructive pulmonary disease (COPD) managed in...
Mon 30 08 2010 Bibliographie
BACKGROUND: Noninvasive positive pressure ventilation (NPPV) provides ventilatory support without the need for an invasive airway approach. Interest has emerged in using NPPV to facilitate earlier removal of an endotracheal...
Mon 30 08 2010 Bibliographie
BACKGROUND: Previous studies of the qualitative sensation of breathlessness have suggested that greater sensory discomfort is reported as airflow obstruction increases. This study investigated relationships between the language of breathlessness...
Mon 30 08 2010 Bibliographie
BACKGROUND: Self-rated health predicts outcome in chronic disease, but such information is scarce in COPD. We aimed to assess self-rated health as an outcome predictor in carefully characterized patients with...
Mon 30 08 2010 Bibliographie
OBJECTIVE: To describe the computed tomography (CT) findings of pulmonary extensively drug-resistant tuberculosis (XDR-TB) in non-HIV-infected patients and to compare them with those of non-XDR multidrug-resistant tuberculosis (MDR-TB). METHODS: Retrospective review...
Mon 30 08 2010 Bibliographie
Observational and randomized studies provide convincing evidence that lung volume reduction surgery (LVRS) improves symptoms, lung function, exercise tolerance, and life span in well-defined subsets of patients with emphysema. Yet, in...
Mon 30 08 2010 Bibliographie
BACKGROUND: We conducted a case-control study in the greater Toronto area to evaluate potential lung cancer risk factors including environmental tobacco smoke (ETS) exposure, family history of cancer, indoor air...
Mon 30 08 2010 Bibliographie
This report describes an endoscopic repair of a tracheal tear with a newly developed optical needle holder. No surgical access was necessary. A 71-year-old woman with a 5-cm gaping iatrogenic tracheal...
Mon 30 08 2010 Bibliographie
Related Articles Sleep and hypertension. Chest. 2010 Aug;138(2):434-43 ...
Sat 28 08 2010 Bibliographie
Related Articles Determinants of treatment outcome after use of the mandibular advancement device in patients with obstructive sleep apnea. ...
Sat 28 08 2010 Bibliographie
Related Articles Continuous positive airway pressure titration for obstructive sleep apnoea: automatic versus manual titration. ...
Sat 28 08 2010 Bibliographie
Related Articles Patients with severe obstructive sleep apnea syndrome and elevated high-sensitivity C-reactive protein need priority treatment. ...
Sat 28 08 2010 Bibliographie
Related Articles Hypoglossal nerve conduction findings in obstructive sleep apnea. Muscle Nerve. 2010 Aug;42(2):257-61 ...
Sat 28 08 2010 Bibliographie
Related Articles Long-term outcome of noninvasive positive pressure ventilation for obesity hypoventilation syndrome. Chest. 2010...
Sat 28 08 2010 Bibliographie
Related Articles Risk factors for atrial fibrillation after lung cancer surgery: analysis of the Society of Thoracic Surgeons general thoracic surgery database....
Sat 28 08 2010 Bibliographie
Comparative mutational profiling in the assessment of lung lesions: should it be the standard of care? ...
Sat 28 08 2010 Bibliographie
Related Articles Nonresected non-small-cell lung cancer in Stages I through IIIB: accelerated, twice-daily, high-dose radiotherapy--a prospective Phase I/II trial with long-term follow-up....
Sat 28 08 2010 Bibliographie
The purpose of this study was to investigate poor prognostic factors in patients with stage IB NSCLC according to the seventh edition TNM classification. METHODS: Between July 1992 and December 2004,...
Fri 27 08 2010 Bibliographie
Our study describes the new seventh edition of the TNM system for lung cancer in a national population and its clinical implications. We classified 1,885 operated patients with lung cancer, reported to the Cancer Registry of Norway (Oslo,…
The patients with non-small cell lung cancer (NSCLC) might contract anemia, however, whether anemia is one of the independent prognostic factors to the patients with NSCLC is still controversial. So the aim of this study is to investigate the correlation…
The use of a combination inhaler containing budesonide and formoterol as both maintenance and quick relief therapy (SMART) has been recommended as an improved method of using inhaled corticosteroid/long-acting β agonist (ICS/LABA) therapy. Published double-blind trials show that budesonide/formoterol therapy…
Background Previous studies have suggested that long-term use of β agonists to treat chronic obstructive pulmonary disease (COPD) may increase the risk of cardiovascular adverse events. In this post hoc analysis, data from the TOwards a Revolution in COPD Health (TORCH)…
Background and aims Although increasing evidence suggests involvement of the distal airway in all stages of asthma, it is not known whether structural changes (defined as airway remodelling) occur in the distal airways of subjects with mild asthma and those with…
Background The mechanisms by which mandibular advancement splints (MAS) improve obstructive sleep apnoea (OSA) are not well understood. This study aimed to evaluate the mechanism of action of MAS by assessing their effect on upper airway structure in patients with OSA. Methods Patients…
Background: Airway inflammation is a key pathological feature of asthma which underlies its clinical presentation. Objectives: To examine whether adding a leukotriene modifier to an inhaled corticosteroid produces further clinical and/or anti-inflammatory benefits in patients symptomatic on short-acting β2-agonists. Methods: Patients uncontrolled on short-acting β2-agonists…
Background: The present study aimed to illustrate differences in characteristics and perception of dyspnea between young atopic adults who have no history of asthma (never-asthmatics) with or without asymptomatic airway hyperresponsiveness (AHR) and those who had childhood asthma and consider themselves…
Background: Multimorbidity is defined as two or more co-existing chronic conditions in an individual and is common in general practice. It is associated with poorer outcomes for patients. This study aimed to establish the prevalence of multimorbidity in patients with chronic…
Whilst recent large-scale studies have provided much evidence on the natural history and therapeutic response in patients with chronic obstructive pulmonary disease (COPD), relatively little is known about the effect in younger patients.We report a pre-specified post-hoc analysis of 356…
We describe a new tool, the Physicians’ Practice Assessment Questionnaire (PPAQ), designed for the global self-assessment of implementation of asthma and COPD guidelines, as determined by the percentage of patients in whom physicians estimate that they implement guidelines key recommendations.…
CONCLUSIONS: Visual inspection of the shape of the FVERVOT provides insight into the hemodynamic basis of PH in a referral PH cohort. MSN is associated with the most severe pulmonary vascular disease and right heart dysfunction. PMID:…
CONCLUSION: TH1-cells directly respond to short-chain LPS. Cigarette smoking suppresses TH1-mediated immune responses to gram-negative bacterial infections by interfering with MyD88/IRAK signalling thereby reducing LPS-induced TLR4-expression. This can explain the increased susceptibility to bacterial infections in COPD. Targeting TLR-signalling might…
Authors: Wanner A, Mendes ES Endothelial dysfunction in the extrapulmonary circulation has been linked to cardiovascular disease. Recent investigations have revealed that in the airway circulation, cigarette smoking, COPD and asthma are also accompanied by endothelial dysfunction.…
CONCLUSIONS: Acetaminophen use may represent an important risk factor for the development and/or maintenance of asthma, rhinoconjunctivitis and eczema in adolescent children. PMID: 20709817 [PubMed - as supplied by publisher] (Source: American Journal of Respiratory and Critical…
CONCLUSIONS: Simvastatin, as an intervention therapy, reverses the pulmonary vascular effects of cigarette smoke, including pulmonary hypertension, and prevents smoke-induced emphysema, but does not prevent small airway remodeling. This is the first demonstration that an intervention can reverse a COPD-associated…
CONCLUSIONS: Despite a lower proportion of pathogens in NV-ICUAP compared with VAP, the type of isolates and outcomes are similar regardless pneumonia is acquired or not during ventilation, indicating they may depend on patientsâ underlying severity rather than previous intubation.…
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