Factors That Prognosticate Mortality In Idiopathic Pulmonary Arterial Hypertension A Systematic Review Of The Literature

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Demographic, Physiologic and Radiographic Characteristics of COPD Patients Taking Chronic Systemic Corticosteroids.

Demographic, Physiologic and Radiographic Characteristics of COPD Patients Taking Chronic Systemic Corticosteroids. COPD. 2012 Feb;9(1):29-35 ...

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Diffusing Capacity for Carbon Monoxide is Linked to Ventilatory Demand in Patients with Chronic Obstructive Pulmonary Disease.

Diffusing Capacity for Carbon Monoxide is Linked to Ventilatory Demand in Patients with Chronic Obstructive Pulmonary Disease. ...

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Nocturnal gastroesophageal reflux, lung function and symptoms of obstructive sleep apnea: Results from an epidemiological survey.

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Systemic CD4+ and CD8+ T cell cytokine profiles correlate with GOLD stage in stable COPD.

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Tissue engineering for pulmonary diseases – insights from the laboratory

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Low‐dose Azithromycin improves phagocytosis of bacteria by both alveolar and monocyte‐derived macrophagesin COPD subjects

Conclusions : The data provide further support for the long term use of low dose azithromycin as an attractive adjunct treatment option for COPD. Improved clearance of both apoptotic cells...

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Efficacy and safety of indacaterol 150 and 300 µg in chronic obstructive pulmonary disease patients from six Asian areas including Japan: A 12‐week, placebo‐controlled study

Conclusions : Indacaterol provided clinically significant bronchodilation and improvements in dyspnoea and health status in Asian COPD patients.

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Evaluation of the asthma control test: A reliable determinant of disease stability and a predictor of future exacerbations

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Obesity, obstructive sleep apnoea and metabolic syndrome

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Efficacy of inhaled N‐acetylcysteine monotherapy in patients with early stage idiopathic pulmonary fibrosis

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Effects of budesonide/formoterol combination therapy versus budesonide alone on airway dimensions in asthma

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New therapy options for MRSA with respiratory infection/pneumonia.

Methicillin-resistant Staphylococcus aureus (MRSA) is a frequent causative agent of nosocomial pneumonia. Because of important clinical consequences of inappropriate treatment, a current review of the potential modifications undergone by S....

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Is healthcare-associated pneumonia a distinct entity needing specific therapy?

Healthcare-associated pneumonia (HCAP) was introduced in 2005 by American Thoracic Society/Infectious Diseases Society of America guidelines as a new entity of pneumonia, resembling nosocomial pneumonia rather than community-acquired pneumonia (CAP)...

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Macrolides for the therapy of nosocomial infections.

Nosocomial infections are an emerging threat. Available solutions are limited due to the multidrug-resistance pattern of the pathogens. Macrolides modulate the immune function of the host and may be active...

Jeu 02 02 2012 Bibliographie

PET imaging of patients with non-small cell lung cancer employing an EGF receptor targeting drug as tracer.

We have previously developed (11)C-erlotinib as a new positron emission tomography (PET) tracer and shown that it accumulates in epidermal growth factor receptor (EGFR)-positive lung cancer xenografts in mice. Here,...

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Diagnosis and management of anaemia and iron deficiency in patients with haematological malignancies or solid tumours in France in 2009-2010: the AnemOnHe study.

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EGFR screening requires good quality tissue, sensitivity and turn-around time (TAT). We report our experience of routine screening, describing sample type, TAT, specimen quality (cellularity and DNA yield), histopathological description,...

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Hot off the breath: triple therapy for idiopathic pulmonary fibrosis--hear the PANTHER roar

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Tests of the Responsiveness of the Chronic Obstructive Pulmonary Disease (COPD) Assessment Test TM (CAT) Following Acute Exacerbation and Pulmonary Rehabilitation.

The chronic obstructive pulmonary disease (COPD) Assessment Test™ (CAT) is an eight-item questionnaire suitable for routine clinical use that shows reliability and validity in stable and exacerbating COPD. METHODS:Study 1 assessed...

Mar 31 01 2012 Bibliographie

Complexity of Medication Use in Newly Diagnosed Chronic Obstructive Pulmonary Disease Patients.

To better understand how medications have been used and the complexity of regimens used to treat patients, we characterized patterns of medication use and the degree to which patients used...

Mar 31 01 2012 Bibliographie

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Mar 31 01 2012 Bibliographie

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Mar 31 01 2012 Bibliographie

Imaging in pulmonary hypertension, part 2: large vessel diseases.

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Mar 31 01 2012 Bibliographie

Chlamydophila pneumonia inhibits the corticosteroid-induced suppressions of metalloproteinase-9 and tissue inhibitor metalloproteinase-1 secretion by human peripheral blood mononuclear cells.

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Inhaled antibiotics for nosocomial pneumonia.

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Factors associated with the initiation of proton pump inhibitors in corticosteroid users.

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Changes in epidemiology, clinical features and severity of influenza A (H1N1) 2009 pneumonia in the first post-pandemic influenza season.
Changes in epidemiology, clinical features and severity of influenza A (H1N1) 2009 pneumonia in the first post-pandemic influenza season. Clin Microbiol Infect. 2011 Dec 8; …
Importance of clinical and echocardiographic hemodynamic assessment in chronic pulmonary embolism.
Importance of clinical and echocardiographic hemodynamic assessment in chronic pulmonary embolism. J Cardiovasc Ultrasound. 2011 Dec;19(4):224-7 Authors:…
Continuous versus intermittent inhaled corticosteroid (budesonide) for mild persistent asthma in children--not too much, not too little
The clinical efficacy of inhaled corticosteroids (ICSs) in asthma has been demonstrated in long-term intervention studies,1 2 and ICSs are recommended first-line treatment of persistent asthma, even in children.3 The long-term benefits of early intervention with ICS have been well…
In search of the fibrotic epithelial cell: opportunities for a collaborative network
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease of unknown aetiology. It has a very poor prognosis and no effective treatment. There are two major barriers to the development of novel treatments in IPF: an incomplete understanding of its…
Continuous versus intermittent inhaled corticosteroids for mild persistent asthma in children: not too much, not too little
The goal of asthma treatment is to prevent exacerbations, achieve daily asthma control and prevent adverse effects with a minimum of medication. In preschoolers, children and adolescents with mild persistent asthma, the most effective therapy remains daily use of low-dose…
Occupational exposure to organic dust increases lung cancer risk in the general population
Background Organic dust is a complex mixture of particulate matter from microbial, plant or animal origin. Occupations with exposure to animal products have been associated with an increased lung cancer risk, while exposure to microbial components (eg, endotoxin) has been associated…
Dyspnoea severity and pneumonia as predictors of in-hospital mortality and early readmission in acute exacerbations of COPD
Background Rates of mortality and readmission are high in patients hospitalised with acute exacerbations of chronic obstructive pulmonary disease (AECOPD). In this population, the prognostic value of the Medical Research Council Dyspnoea Scale (MRCD) is uncertain, and an extended MRCD (eMRCD)…
An Association Between Neutrophils and Immunoglobulin Free Light Chains in the Pathogenesis of COPD.
CONCLUSION: This study describes for the first time an association between neutrophils and IgLC in the pathophysiology of COPD, which could open new avenues to targeted treatment of this chronic disease. PMID: 22227380 [PubMed - as supplied…
Anaphylaxis as an adverse event following immunisation in the UK and Ireland.
Anaphylaxis is a rare adverse event following immunisation (AEFI) and unlikely to be detected in prelicensure vaccine trials. Previous retrospective studies have been hampered by the paucity of information available to passive reporting schemes. The aim of the present study was…
Inflammation and Coagulation in Urticaria and Angioedema.
Urticaria is a skin disease characterised by short-lived surface swellings of the dermis (wheals) frequently accompanied by itching. It is classified as acute or chronic depending on whether the wheal recurrence occurs for less or more than six weeks. Acute…
The Role of Natural Killer T Cells in the Pathogenesis of Acute Exacerbation of Human Asthma.
Natural killer T (NKT) cells have been reported to play a crucial role in the pathogenesis of asthma in a mouse model of acute asthma. The present study aimed to investigate the role of NKT cells in the immune pathogenesis…
Basophil Activation Test in Allergy: Time for an Update?
A wide range of reported evidence in the literature has shown that the quantification of basophil activation by flow cytometry (basophil activation test, BAT) has proven to be a useful tool for the assessment of immediate-type responses to allergens mediated…
Psychosocial stress and asthma morbidity.
Psychosocial stress and asthma morbidity. Curr Opin Allergy Clin Immunol. 2012 Jan 19; Authors: Yonas MA, Lange…
The regulation of fibrosis in airway remodeling in asthma.
The regulation of fibrosis in airway remodeling in asthma. Mol Cell Endocrinol. 2012 Jan 14; Authors: Royce…
Omalizumab beyond asthma.
Omalizumab beyond asthma. Allergol Immunopathol (Madr). 2012 Jan 18; Authors: Sanchez J, Ramirez R, Diez S, Sus…

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Factors that prognosticate mortality in idiopathic pulmonary arterial hypertension: A systematic review of the literature☆

Sep

2010

Factors that prognosticate mortality in idiopathic pulmonary arterial hypertension: A systematic review of the literature☆

There is a lack of consensus on factors that predict mortality in idiopathic pulmonary arterial hypertension (IPAH). Tests that can accurately predict prognosis are needed to guide treatment and counsel patients.

Methods: We conducted a systematic review to identify factors that prognosticate mortality in IPAH. Study design, cohort size, comparison method, measured value, and statistical significance was extracted for eight pre-selected parameters [pulmonary vascular resistance (PVR), mean pulmonary arterial pressure (mPAP), mean right atrial pressure (mRAP), cardiac output, right ventricular end diastolic pressure, functional class, 6 min walk distance (6MWD), and diffusing capacity of carbon monoxide]. Results: 107 factors have been associated with mortality in...

Authors : John Robert, Swiston , Sindhu R., Johnson , John T., Granton
Publication year: 2010
Source: Respiratory Medicine, In Press, Corrected Proof, Available online 31 August 2010
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Factors that prognosticate mortality in idiopathic pulmonary arterial hypertension: A systematic review of the literature☆ Top